MS1943 from CAYMAN CHEMICAL COMPANY
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| Product Name | MS1943 |
| Description | A PROTAC that drives EZH2 degradation; inhibits EZH2 (IC50 = 120 nM) and is selective for EZH2 over EZH1, as well as a panel of 45 kinases at 10 µM; induces EZH2 degradation and reduces H3K27me3, as well as induces activation of the unfolded protein response pathway in MDA-MB-468 TNBC cells at 4 µM; inhibits the growth of MDA-MB-468 cells in vitro (GI50 = 2.2 µM); reduces tumor volume in an MDA-MB-468 mouse xenograft model at 50 mg/kg |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | MS-1943 EZH MDAMB468 MDAMB |
| Gene, Accession, CAS # | CAS: 2225938-17-8 |
| Catalog # | 35466-10 |
| Price | $622.00 |
| Order / More Info | MS1943 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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