IT1t (hydrochloride) from CAYMAN CHEMICAL COMPANY

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Product NameIT1t (hydrochloride)
DescriptionA CXCR4 antagonist (IC50s = 8 and 11 nM for the human and rat receptors, respectively); selective for CXCR4 over hERG/Kv11.1 (IC50 = 13,240 nM); inhibits CXCL12-induced calcium mobilization in CEM cells (IC50 = 1.1 nM) and decreases CXCL12-induced migration of Jurkat cells (IC50 = 79.1 nM); inhibits replication of the HIV-1 strain NL4-3 in MT-4 cells and isolated PHA-stimulated PBMCs; reduces tumor growth in an MDA-MB-231-B zebrafish xenograft model at 20 µM
Size10 mg
Concentrationn/a
Applicationsn/a
Other Names864677-55-4 1258011-83-4 IT 1t CXC CCR 4 CXCL 12 HIV1 NL43 43 MT4 MDAMB231B MDAMB 231B MDAMB231
Gene, Accession, CAS #CAS: 1092776-63-0
Catalog #28434-10
Price$195.00
Order / More InfoIT1t (hydrochloride) from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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