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Product Name | CP 154,526 (hydrochloride) |
Description | An antagonist of CRF1 (Ki = 2.7 nM); selective for CRF1 over CRF2 (Ki = >10 µM); inhibits CRF-induced increases in ACTH levels in rat plasma (ID50 = 10 mg/kg); increases the time spent in the open arms of the elevated plus maze in rats at 1 mg/kg; decreases immobility time in the forced swim test in a rat model of depressive-like behavior at 10 mg/kg, twice per day for 14 days; decreases stress-induced reinstatement of cocaine or heroin self-administration in cocaine- and heroin-trained rats, respectively, at 15 and 30 mg/kg, |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 157286-86-7 CP154526 CP-154526 CRF-1 2 HCl CP154,526 |
Gene, Accession, CAS # | CAS: 257639-98-8 |
Catalog # | 20732-1 |
Price | $61.00 |
Order / More Info | CP 154,526 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |