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Product Name | MS 245 (oxalate) |
Description | An antagonist of 5-HT6 (Ki = 2.3 nM for the human recombinant receptor); selective for 5-HT6 over 5-HT2A and 5-HT2C receptors (Kis = 130 and 23 nM, respectively), as well as 5-HT1A, 5-HT1B, 5-HT1E, 5-HT3, and 5-HT7 receptors (Kis = 720, 9,200, 4,220, 2,390, and 600 nM, respectively); decreases cAMP production induced by 5-HT in HEK293 cells expressing 5-HT6 (pA2 = 8.88 nM); potentiates drug discrimination induced by (+)-amphetamine, but has no effect on cocaine or (-)-nicotine (Item No. 20887) drug discrimination in rats at 5 mg/kg ,, |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | MS245 5HT-6 2A 2C 1A 1B 1E 3 7 5HT6 5HT2A 5HT2C 5HT1A 5HT1B 5HT1E 5HT3 5HT7 HEK-293 |
Gene, Accession, CAS # | CAS: 275363-58-1 |
Catalog # | 11936-1 |
Price | $37.00 |
Order / More Info | MS 245 (oxalate) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |