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Product Name | ASP7663 |
Description | A TRPA1 agonist; induces calcium influx in HEK293 cells expressing human, rat, or mouse TRPA1 (EC50s = 0.51, 0.54, and 0.5 µM, respectively) and stimulates 5-HT release from QGP-1 enterochromaffin cells that endogenously express TRPA1 (EC50 = 72.5 µM); reduces colonic transit time in clonidine- or loperamide-induced mouse models of constipation at 1 mg/kg; reduces the number of abdominal contractions induced by colorectal distension in mice at 0.3 mg/kg |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | ASP 7663 TRPA 1 HEK 293 5HT QGP1 entero chromaffin HC030031 |
Gene, Accession, CAS # | CAS: 1190217-35-6 |
Catalog # | 31122-1 |
Price | $33.00 |
Order / More Info | ASP7663 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |