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Product Name | BMS 813160 |
Description | A dual antagonist of CCR2 and CCR5 (IC50s = 6.2 and 3.6 nM, respectively, in radioligand binding assays); inhibits chemotaxis induced by the CCR2 ligand MCP-1 in THP-1 cells the CCR5 ligand MIP-1β in isolated peripheral T cells (IC50s = 0.8 and 1.1 nM, respectively); dose-dependently inhibits peritoneal monocyte and macrophage infiltration in an hCCR-2 KI mouse model of thioglycolate-induced peritonitis, with 54% inhibition at 50 mg/kg twice per day |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | BMS813160 CCR 5 THP1 MIP1β hCCR2 MCP1 |
Gene, Accession, CAS # | CAS: 1286279-29-5 |
Catalog # | 28421-5 |
Price | $965.00 |
Order / More Info | BMS 813160 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |