BMS 813160 from CAYMAN CHEMICAL COMPANY

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Product NameBMS 813160
DescriptionA dual antagonist of CCR2 and CCR5 (IC50s = 6.2 and 3.6 nM, respectively, in radioligand binding assays); inhibits chemotaxis induced by the CCR2 ligand MCP-1 in THP-1 cells the CCR5 ligand MIP-1β in isolated peripheral T cells (IC50s = 0.8 and 1.1 nM, respectively); dose-dependently inhibits peritoneal monocyte and macrophage infiltration in an hCCR-2 KI mouse model of thioglycolate-induced peritonitis, with 54% inhibition at 50 mg/kg twice per day
Size5 mg
Concentrationn/a
Applicationsn/a
Other NamesBMS813160 CCR 5 THP1 MIP1β hCCR2 MCP1
Gene, Accession, CAS #CAS: 1286279-29-5
Catalog #28421-5
Price$965.00
Order / More InfoBMS 813160 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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