Vortioxetine (hydrobromide) from CAYMAN CHEMICAL COMPANY
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| Product Name | Vortioxetine (hydrobromide) |
| Description | A multimodal serotonergic agent; inhibits 5-HT reuptake (Ki = 1.6 nM); binds to the 5-HT1A, 5-HT1B, 5-HT3A, and 5-HT7 receptors (Kis = 15, 33, 3.7, and 19 nM, respectively); binds to the β1-adrenergic receptor (Ki = 46 nM); acts as an antagonist at 5-HT3A and 5-HT7, a partial agonist at 5-HT1B, and a full agonist at 5-HT1A receptors; selective for SERT over the dopamine and norepinephrine transporters (IC50s = 5.3, 890, and 140 nM, respectively); increases 5-HT levels in vivo in rat brain and decreases occupancy at SERT when administered at a dose of 5 or 10 mg/kg per day; has antidepressant-like and anxiolytic-like effects in mice at 5 mg/kg but not 10 mg/kg |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 508233-74-7 Lu AA21004 LuAA21004 Lu-AA-21004 LuAA-21004 5HT 5HT1A 5HT-1A 5HT1B 5HT-1B 5HT3A 5HT3A 5HT7 5HT-7 b1 b-1 H-2 b2 b-2 5HT2C 5HT-2C 5HT6 5HT-6 5-HT-1A 5-HT-1B 5-HT-3A 5-HT-7 5-HT-2C 5-HT-6 anti-depressant Brintellix Trintellix GPCR SSRI |
| Gene, Accession, CAS # | CAS: 960203-27-4 |
| Catalog # | 23694-10 |
| Price | $129.00 |
| Order / More Info | Vortioxetine (hydrobromide) from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY