Ro 67-7476 from CAYMAN CHEMICAL COMPANY
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| Product Name | Ro 67-7476 |
| Description | A positive allosteric modulator of mGluR1; enhances glutamate-induced calcium release in HEK293 cells expressing rat mGluR1a (EC50 = 1.74 µM); selective for rat mGluR1 over rat mGluR2, mGluR4, and mGluR8 at 10 µM; increases the amplitude of mGluR1 EPSCs evoked by 2,3-dihydroxy-6-nitro-7-sulfamoylbenzoquionxaline, picrotoxin, or AP5 in the Purkinje cells of rat cerebellar slices; activates ERK1/2 phosphorylation in the absence of exogenously added glutamate (EC50 = 163.3 nM), |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Ro67-7476 Ro677476 Ro-677476 mGluR-1 1a 2 4 8 HEK-293 AP-5 ERK2 ERK-1 |
| Gene, Accession, CAS # | CAS: 298690-60-5 |
| Catalog # | 11993-10 |
| Price | $214 |
| Order / More Info | Ro 67-7476 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
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