TAS 0728 from CAYMAN CHEMICAL COMPANY
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| Product Name | TAS 0728 |
| Description | A covalent HER2 inhibitor (IC50 = 36 nM); selective for HER2 over panels of 386 and 374 additional kinases, as well as a panel of 68 non-kinase enzymes, at 1 µM; inhibits HER2 autophosphorylation in HER2-overexpressing SK-BR-3 cells; inhibits the growth of six HER2-amplified cancer cell lines (GI50s = 1.6-31 nM); reduces tumor volume in NCI N87 and BT474 mouse xenograft models |
| Size | 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | TAS0728 HER-2 nonkinase SKBR BR3 SKBR3 A-431 NCIN87 BT-474 |
| Gene, Accession, CAS # | CAS: 2088323-16-2 |
| Catalog # | 33528-25 |
| Price | $838.00 |
| Order / More Info | TAS 0728 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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