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Product Name | AA43279 |
Description | An Nav1.1 activator (EC50 = 9.5 µM in a patch-clamp assay using HEK293 cells expressing the human channel); selective for Nav1.1 over Nav1.4 and Nav1.7 at 30 µM but also activates Nav1.2, Nav1.5, and Nav1.6 (EC50s = 22.8, 14.4, and 11.6 µM, respectively); inhibits IKKβ (IC50 = 2.9 µM); increases the seizure threshold in the MEST test in mice at 300 mg/kg |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | AA-43279 Nav 1.4 1.7 1.2 1.5 1.6 HEK-293 |
Gene, Accession, CAS # | CAS: 354812-16-1 |
Catalog # | 40428-50 |
Price | $343.00 |
Order / More Info | AA43279 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |