LY393558 from CAYMAN CHEMICAL COMPANY
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| Product Name | LY393558 |
| Description | A serotonin reuptake inhibitor (IC50 = 3.3 nM in rat cortical synaptosomes); selective for serotonin reuptake over norepinephrine reuptake in rat cortical synaptosomes (IC50 = 2,510 nM); inhibits 5-HT-induced [35S]GTPγS binding in cells expressing human 5-HT1B or 5-HT1D receptors (Kbs = 0.89 and 10.4 nM, respectively); reduces pulmonary vascular remodeling, increases in right ventricular systolic pressure, and the development of right ventricular hypertrophy in a mouse model of pulmonary arterial hypertension at 30 mg/kg per day |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 388123-96-4 LY 393558 5HT 1B 1D 35 |
| Gene, Accession, CAS # | CAS: 271780-64-4 |
| Catalog # | 32775-5 |
| Price | $90.00 |
| Order / More Info | LY393558 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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