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Product Name | Tasisulam |
Description | An anticancer agent; inhibits the growth of Calu-6 NSCLC and A-375 melanoma cell lines (EC50s = 10 and 25 µM, respectively); induces arrests the cell cycle at the G2/M phase and induces apoptosis of Calu-6 cells in a concentration-dependent manner; induces non-apoptotic growth arrest in HUVECs and inhibits VEGF-, FGF-, and EGF-induced endothelial cord formation in vitro (EC50s = 47, 103, and 34 nM, respectively); reduces hemoglobin content and blood vessel density in a Matrigel™ plug model of neoangiogenesis; reduces tumor growth in a dose-dependent manner in a Calu-6 mouse xenograft model |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | LY573636 |
Gene, Accession, CAS # | CAS: 519055-62-0 |
Catalog # | 21556-50 |
Price | $321.00 |
Order / More Info | Tasisulam from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |