Edit |   |
---|---|
Product Name | CP 671,305 |
Description | A potent PDE4D inhibitor (IC50 = 3 nM); selective for PDE4D over PDE4A, -B, and -C (IC50s = 310, 287, and 3,858 nM, respectively), as well as over PDE1-3 and 5 (IC50s = >5,000 nM for all); inhibits release of LTE4 from eosinophils (IC50 = 52 nM) and LTB4 from neutrophils (IC50 = 106 nM); inhibits antigen-induced pulmonary eosinophil influx in cynomolgus monkeys in a dose-dependent manner |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | CP671,305 671305 CP671305 PDE-4D 4 D 4A A PDE4B PDE4C 4B 4C PDE13 LTE LTB |
Gene, Accession, CAS # | CAS: 445295-04-5 |
Catalog # | 26743-1 |
Price | $44.00 |
Order / More Info | CP 671,305 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |