Motolimod from CAYMAN CHEMICAL COMPANY
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| Product Name | Motolimod |
| Description | A TLR8 agonist; increases the production of TNF-α and IL-12 in human PBMCs (EC50s = 140 and 120 nM, respectively), monocytes, and dendritic cells; increases cytolysis in K562 NK cell-sensitive leukemia cells at 167 and 500 nM for 48 hours; increases plasma levels of a group of human cytokines , including IL-6, IL-12p70, TNF-α, MCP-1, and MIP-1β, in NSG-HIS mice at 1.5 and 15 mg/m2; reduces tumor growth and increases tumor infiltration of monocytes and T cells in an ovarian cancer NSG-HIS mouse model |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | VTX-2337 |
| Gene, Accession, CAS # | CAS: 926927-61-9 |
| Catalog # | 22952-1 |
| Price | $33.00 |
| Order / More Info | Motolimod from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY