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Product Name | Enfuvirtide |
Description | A biomimetic peptide inhibitor of HIV-1 fusion with CD4+ cells; inhibits HIV-1 infectivity of HeLa cells stably expressing CD4 by the HXB2 strain (IC50 = 692 pM) and by clinical isolates (IC90s = 6.1-61 nM) in a single-cycle infectivity assay; inhibits genomic integration of HIV-1 into human intraepithelial vaginal cells and PBMCs (IC50s = 51.2 and 13.58 µM, respectively); binds to a recombinant molecular mimic of HIV-1 glycoprotein gp41 (Kd = 32 nM); binds to recombinant FPRs expressed in rat basophilic leukemia cells (IC50 = 5 nM) and attracts and activates human peripheral blood phagocytes, but not T lymphocytes, in vitro (100 nM) |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | HIV1 CD-4 HXB-2 gp-41-127-162AA fuzeon pentafuside GP 41-127-162AA GP 41127162AA GP41127162AA T-20 T20 DP-178 DP178 ENF |
Gene, Accession, CAS # | CAS: 159519-65-0 |
Catalog # | 24097-10 |
Price | $199.00 |
Order / More Info | Enfuvirtide from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |