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Product Name | CRT0066854 |
Description | A PKCι and PKCζ inhibitor (IC50s = 132 and 639 nM, respectively); an inhibitor of ROCK2 (IC50 = 620 nM); is selective for PKCι, PKCζ, and ROCK2 over typical PKCs and 98 other kinases in a panel at 1 µM; decreases viability of A549 lung carcinoma cells (IC50 = 3.47 µM); decreases colony formation in HeLa cells by 65% at 1 µM; impairs lumen formation in MDCK cells in a Matrigel™ assay and migration of NRK-49F cells in a wound assay |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | CRT-0066854 PKC-ι ζ ROCKII LLGL-2 HEK-293 A-549 NRK49F 49-F NRK49 |
Gene, Accession, CAS # | CAS: 1438881-19-6 |
Catalog # | 28463-1 |
Price | $49.00 |
Order / More Info | CRT0066854 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |