Entacapone from CAYMAN CHEMICAL COMPANY
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| Product Name | Entacapone |
| Description | A reversible COMT inhibitor (IC50s = 10, 10, 20, and 160 nM for rat duodenum, brain, erythrocyte, and liver COMT, respectively); selective for COMT over MAO-A, MAO-B, PST-M, and PST-P (IC50s = >50 µM); in combination with L-DOPA and carbidopa, reduces 3-OMD levels in the rat striatum and hypothalamus to 52 and 27%, respectively, of the levels in control animals receiving only L-DOPA and carbidopa; in combination with L-DOPA and benserazide, increases contralateral turning behavior and striatal extracellular dopamine levels in a 6-OHDA rat model of Parkinson's disease; inhibits contraction of colon longitudinal muscle explants from a 6-OHDA rat model of Parkinson's disease (EC50 = 200 µM) |
| Size | 50 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | OR-611 |
| Gene, Accession, CAS # | CAS: 130929-57-6 |
| Catalog # | 14153-50 |
| Price | $121.00 |
| Order / More Info | Entacapone from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY