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Product Name | 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC |
Description | Ubiquitous lipid species generated following PLA2 hydrolysis of phosphatidylcholine; increases the production of ROS and decreases SOD and eNOS protein levels and phosphorylation of ERK1/2 in HUVECs at 125 µM; potentiates the secretion of IL-6, IL-1β, IL-12, and TNF-α in LPS-stimulated M1 macrophages, but has no effect on CD163, CD206, CD36, or IL-10 in LPS-stimulated M2 macrophages at 0.3-1.0 µM; increases TGF-β1 production and enhances Foxp3 protein levels in Treg cells in isolated human peripheral blood at 10 µM; enhances neutrophil function, bacterial clearance, and survival in mouse models of sepsis at 10 mg/kg. |
Size | 500 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 16:0/0:0-PC|1-Hexadecanoyl-sn-glycero-3-Phosphatidylcholine|1-Hexadecanoyl-sn-glycero-3-Phosphocholine|1-Hexadecanoyl-sn-glycerol-3-Phosphorylcholine|1-Palmitoyl-sn-glycero-3-Phosphocholine|PC(16:0/0:0) |
Gene, Accession, CAS # | CAS: 17364-16-8 |
Catalog # | 10172-500 |
Price | $238.00 |
Order / More Info | 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |