GSK-J4 (hydrochloride) from CAYMAN CHEMICAL COMPANY
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| Product Name | GSK-J4 (hydrochloride) |
| Description | An ethyl ester prodrug of the JMJD3 selective histone demethylase inhibitor GSK-J1; reduces LPS-induced proinflammatory cytokine production, including that of TNFα (IC50 = 9 µM) in human primary macrophages |
| Size | 50 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 1373423-53-0 epigenetics demethylase histones JMJD3 cells differentiation developments inflammation cancers GSK-J1 pro-drug prodrugs H3 lysine 27 H3K27 H3K-27 GSKJ1 GSKs J1 GSKJ4 J4 inhibitors inhibits inhibitions macrophages reduce LPS induce induced proinflammatory inflammatory pro pro-inflammatory cytokines TNF.alpha. TNF-.alpha. TNF .alpha. TNF-alpha TNF-a TNF-α TNFalpha TNFa TNFα alpha α HCl Structural Genomic Consortium SGC |
| Gene, Accession, CAS # | CAS: 1797983-09-5 |
| Catalog # | 12073-50 |
| Price | $302.00 |
| Order / More Info | GSK-J4 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY