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Product Name | Glyburide (potassium salt) |
Description | A sulfonylurea; an inhibitor of SUR1 linked to Kir6.2 (IC50 = 4.3 nM); binds to RINm5F microsomes (Kd = 0.3 nM); inhibits 86Rb+ efflux from intact RINm5 cells (K0.5 = 0.06 nM); reduces blood glucose levels and increases the activity of hepatic GST and G6PDH in an STZ-induced rat model of diabetes at 5 mg/kg; inhibits ATP-induced increases in caspase-1 activation and IL-1β and IL-18 secretion in a concentration-dependent manner in LPS-primed BMDMs; reduces lesion growth in mice infected with L. mexicana at 80 mg/ml |
Size | 10 g |
Concentration | n/a |
Applications | n/a |
Other Names | Glibenclamide |
Gene, Accession, CAS # | CAS: 52169-36-5 |
Catalog # | 15009-10 |
Price | $173.00 |
Order / More Info | Glyburide (potassium salt) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |