S-72 from CAYMAN CHEMICAL COMPANY

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Product NameS-72
DescriptionAn inhibitor of microtubule polymerization; inhibits microtubule polymerization in a cell-free assay at 1, 3, and 10 µM; reduces viability in MCF-7 and paclitaxel-resistant MCF-7/T cells (IC50s = 15.64 and 26.32 nM, respectively); inhibits migration and invasion, as well as the percentage of wound closure in a scratch assay in MCF-7 and MCF-7/T cells at 50 nM; induces cell cycle arrest at the G2/M phase in MCF-7/T cells and induces apoptosis in those same cells at 100 nM; inhibits STING activation in MCF-7/T cells at 100 nM; inhibits tumor growth in MCF-7/T and MX-1/T mouse xenograft models of paclitaxel-resistant breast cancer at 15 mg/kg per day
Size25 mg
Concentrationn/a
Applicationsn/a
Other Namesmicro tubule S72 MCF7 MCF7T MX1T MX1
Gene, Accession, CAS #CAS: 2446799-14-8
Catalog #39083-25
Price$272.00
Order / More InfoS-72 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
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http://www.caymanchem.com

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