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Product Name | S-72 |
Description | An inhibitor of microtubule polymerization; inhibits microtubule polymerization in a cell-free assay at 1, 3, and 10 µM; reduces viability in MCF-7 and paclitaxel-resistant MCF-7/T cells (IC50s = 15.64 and 26.32 nM, respectively); inhibits migration and invasion, as well as the percentage of wound closure in a scratch assay in MCF-7 and MCF-7/T cells at 50 nM; induces cell cycle arrest at the G2/M phase in MCF-7/T cells and induces apoptosis in those same cells at 100 nM; inhibits STING activation in MCF-7/T cells at 100 nM; inhibits tumor growth in MCF-7/T and MX-1/T mouse xenograft models of paclitaxel-resistant breast cancer at 15 mg/kg per day |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | micro tubule S72 MCF7 MCF7T MX1T MX1 |
Gene, Accession, CAS # | CAS: 2446799-14-8 |
Catalog # | 39083-25 |
Price | $272.00 |
Order / More Info | S-72 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |