ARN810 from CAYMAN CHEMICAL COMPANY

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Product NameARN810
DescriptionA SERD; binds to ERα and ERβ (IC50s = 6.1 and 8.8 nM, respectively); induces degradation of ERα in MCF-7 cells (EC50 = 0.7 nM); inhibits 17β-estradiol-induced ERα transcriptional activity in a reporter assay and reduces MCF-7 breast cancer cell viability (IC50 = 2 nM); inhibits 17β-estradiol-induced uterine weight gain in rats at 1 mg/kg; reduces tumor volume in tamoxifen-sensitive and -resistant MCF-7 mouse xenograft models
Size10 mg
Concentrationn/a
Applicationsn/a
Other NamesGDC-0810|RG-6046
Gene, Accession, CAS #CAS: 1365888-06-7
Catalog #29595-10
Price$223.00
Order / More InfoARN810 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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