CADD522 from CAYMAN CHEMICAL COMPANY
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| Product Name | CADD522 |
| Description | An inhibitor of RUNX2-DNA binding; inhibits RUNX2 binding to OSE2 oligonucleotides in a cell-free assay, as well as inhibits RUNX2 enrichment on MMP-13 promoters in MCF-7 cells from 100-1,000 nM; decreases clonogenic survival in a panel of nine breast cancer cell lines at 50 µM; decreases the expression of MMP-13 and VEGF in ectopic RUNX2-expressing T47D-RUNX2 and MCF-7-RUNX2 cells; reduces tumor volume and incidence in the MMTV-PyMT transgenic mouse model of breast cancer at 20 mg/kg |
| Size | 100 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | CADD-522 RUN OSE MMP13 MCF7 MMP13 T47DRUNX2 MMTVPyMT MCF7RUNX2 |
| Gene, Accession, CAS # | CAS: 199735-88-1 |
| Catalog # | 36679-100 |
| Price | $438.00 |
| Order / More Info | CADD522 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY