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Product Name | Methylnaltrexone (bromide) |
Description | A peripherally restricted μ-opioid receptor antagonist (Ki = 10 nM; IC50s = 130.7 and 0.43 nM in rat brain membranes prepared with sodium chloride or water, respectively); selective for μ-opioid receptors over δ- and κ-opioid receptors (Kis = 630.95 and 31.62 nM, respectively); decreases spontaneous mechanical activity in ileum isolated from morphine-treated guinea pigs when administered at doses of 1 and 10 µM; does not inhibit heroin self-administration in rats; does not induce withdrawal syndrome in morphine-dependent rhesus monkeys when administered at doses up to 32 mg/kg |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | MRZ 2663BR|Naltrexone methylbromide |
Gene, Accession, CAS # | CAS: 73232-52-7 |
Catalog # | 24072-1 |
Price | $32.00 |
Order / More Info | Methylnaltrexone (bromide) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |