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Product Name | CAY10795 |
Description | A 15-PGDH inhibitor (IC50 = 3 nM); increases PGE2 levels >3-fold in IL-1β-stimulated A549 cells at 500 nM; reduces 15-PGDH activity in the colon of mice at 20 mg/kg and limits decreases in body weight and colon length and reduces colon ulceration in a mouse model of DSS-induced ulcerative colitis at 40 mg/kg; accelerates recovery of circulating neutrophils following whole-body radiation and bone marrow transplant in mice at 10 mg/kg twice per day |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 15-hydroxy Prostaglandin Dehydrogenase Inhibitor|15-PGDH Inhibitor |
Gene, Accession, CAS # | CAS: 2241676-74-2 |
Catalog # | 37981-10 |
Price | $565.00 |
Order / More Info | CAY10795 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |