Edit |   |
---|---|
Product Name | CAIX Inhibitor S4 |
Description | A CAIX inhibitor (Ki = 0.007 µM for the recombinant human enzyme); selective for CAIX over CAI and CAII but does inhibit CAXII (Kis = 5.6, 0.55, and 0.002 µM, respectively); inhibits proliferation of HT-29 and MDA-MB-231, but not HCT116, cancer cells under anoxic conditions (IC50s = 20, 481, and >1,000 µM, respectively); reduces the number of lung metastases, but not primary tumor growth, in an MDA-MB-231 mouse xenograft model at 10 mg/kg |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | S 4 HT29 HCT 116 MDAMB 231 MDAMB231 |
Gene, Accession, CAS # | CAS: 1330061-67-0 |
Catalog # | 31119-25 |
Price | $336.00 |
Order / More Info | CAIX Inhibitor S4 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |