(±)-trans-ACPD from CAYMAN CHEMICAL COMPANY
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| Product Name | (±)-trans-ACPD |
| Description | An agonist of mGluRs (EC50s = 15, 2, 40, 23, and 82 µM for mGluR1, -2, -3, -5, and -6, respectively, in CHO cells expressing recombinant receptors, and ~800 µM for mGluR4 in baby hamster kidney cells); increases cAMP accumulation in adult rat cerebral cortex slices (EC50 = 47.8 µM) but not in isolated rat embryonic neurons or neonatal glial cells at 1-1,000 µM; increases phosphoinositide hydrolysis in neonatal rat cerebral cortex and hippocampal slices at 10-1,000 µM; induces convulsions in neonatal rats (ED50 = 100 mg/kg), an effect that can be reversed by administration of the NMDA receptor antagonists LY233053 and LY274614 |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 39026-63-6 39026-64-7 56827-69-1 207729-09-7 m GluR mGlu R AC PD mGluR2 mGluR3 mGluR5 mGluR6 AMP LY 233053 274614 |
| Gene, Accession, CAS # | CAS: 67684-64-4 |
| Catalog # | 28849-10 |
| Price | $213.00 |
| Order / More Info | (±)-trans-ACPD from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY