Edit |   |
---|---|
Product Name | Prinomastat |
Description | An inhibitor of MMP-2, -3, -9, -13, and -14 (IC50s = 0.05, 0.3, 0.26, 0.03, and 0.33 nM, respectively); selective for these MMPs over MMP-1 and MMP-7 (IC50s = 8.3 and 54 nM, respectively); reduces tumor growth and inhibits the formation of lung metastases in a murine Lewis lung carcinoma model at 50 mg/kg; reduces the incidence of lung metastasis and tumor microvessel density in an NCI H460 lung cancer orthotopic mouse model at 100 mg/kg; reduces BALF levels of TNF-α and pulmonary edema in a rat model of ventilator-induced lung injury |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | AG-3340|KB-R9896 |
Gene, Accession, CAS # | CAS: 192329-42-3 |
Catalog # | 37699-1 |
Price | $30 |
Order / More Info | Prinomastat from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |