Edit |   |
---|---|
Product Name | GLPG1837 |
Description | A CFTR potentiator; increases forskolin-induced opening of wild-type and mutant CFTRs expressing the F508del and G551D missense mutations with EC50 values of 88, 3, and 339 nM, respectively, in a reporter assay; increases forskolin-induced conductivity of patient-derived bronchial epithelial cells expressing both F508del- and G551D-mutant CFTRs (EC50 = 159 nM in a TECC assay) |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | ABBV-974 |
Gene, Accession, CAS # | CAS: 1654725-02-6 |
Catalog # | 9003143-5 |
Price | $193.00 |
Order / More Info | GLPG1837 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |