BMS 986020 from CAYMAN CHEMICAL COMPANY
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| Product Name | BMS 986020 |
| Description | An LPA1 receptor antagonist (Kb = 0.0067 µM); selective for LPA1 over LPA3 in CHO cells expressing the human receptors (IC50s = 0.3 and >1 µM, respectively); inhibits OATP1B1, OATP1B3, BSEP, MDR3, MRP3, and MRP4 (IC50s = 0.17, 0.57, 4.8, 7.5, 22, and 6.2 µM, respectively); reduces bleomycin-induced lung fibrosis in rats at 30 mg/kg twice per day; decreases total biliary bile acid levels and induces bile duct hyperplasia, cholangitis, and cholestasis in monkeys at 225 and 500 mg/kg per day; decreases infarct volume and neurological deficits in a mouse model of transient MCAO-induced ischemic stroke at 5 mg/kg |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | AM-000152 |
| Gene, Accession, CAS # | CAS: 1257213-50-5 |
| Catalog # | 22049-1 |
| Price | $61.00 |
| Order / More Info | BMS 986020 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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