CY-09 from CAYMAN CHEMICAL COMPANY
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| Product Name | CY-09 |
| Description | An NLRP3 inhibitor; binds to the ATP-binding motif of NLRP3 NACHT domain (Kd = 500 nM); selectively inhibits NLRP3 ATPase activity over the ATPase activity of NLRP1, NLRC4, NOD2, and RIG-I at 1 µM; suppresses NLRP3 inflammasome assembly; inhibits nigericin-induced NLRP3 inflammasome activation in THP-1 cells at 1 µM; improves the LVEF and LVFS and reduces myocardial fibrosis in a mouse model of myocardial infarction induced by LAD coronary artery occlusion at 5 mg/kg; reduces hepatic steatosis in a high-fat diet-induced NAFLD mouse model at a dose of 2.5 mg/kg |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | CY09 NLRP 3 1 NLRC 4 NOD 2 RIGI THP1 |
| Gene, Accession, CAS # | CAS: 1073612-91-5 |
| Catalog # | 33353-10 |
| Price | $176.00 |
| Order / More Info | CY-09 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY