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Product Name | TLR7/8 Agonist 1 (hydrochloride) |
Description | A dual agonist of TLR7 and TLR8 (EC50s = 50 and 55 nM, respectively, in cell-based assays); increases the levels of TNF-α, IFN-γ, IL-12p40, and CCL4 in PBMCs in a biphasic manner; increases serum levels of IL-12p40 and CXCL10, as well as the number of dendritic cells per injection-site proximal lymph node, in mice at 25 nmol; has been conjugated to various fluorophores as TLR7 probes and to polymer particles for the modulation of adjuvant activity |
Size | 500 µg |
Concentration | n/a |
Applications | n/a |
Other Names | ?Toll-Like Receptor 7/8 Agonist 1 |
Gene, Accession, CAS # | CAS: 1620278-72-9 |
Catalog # | 28451-500 |
Price | $73.00 |
Order / More Info | TLR7/8 Agonist 1 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |