TLR7/8 Agonist 1 (hydrochloride) from CAYMAN CHEMICAL COMPANY

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Product NameTLR7/8 Agonist 1 (hydrochloride)
DescriptionA dual agonist of TLR7 and TLR8 (EC50s = 50 and 55 nM, respectively, in cell-based assays); increases the levels of TNF-α, IFN-γ, IL-12p40, and CCL4 in PBMCs in a biphasic manner; increases serum levels of IL-12p40 and CXCL10, as well as the number of dendritic cells per injection-site proximal lymph node, in mice at 25 nmol; has been conjugated to various fluorophores as TLR7 probes and to polymer particles for the modulation of adjuvant activity
Size500 µg
Concentrationn/a
Applicationsn/a
Other Names?Toll-Like Receptor 7/8 Agonist 1
Gene, Accession, CAS #CAS: 1620278-72-9
Catalog #28451-500
Price$73.00
Order / More InfoTLR7/8 Agonist 1 (hydrochloride) from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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