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Product Name | Dehydroandrographolide |
Description | A diterpene with diverse biological activities; inhibits DNA replication of HBV in HepG2 2.2.15 cells (IC50 = 22.6 µM); inhibits ANO1 chloride currents in Fisher rat thyroid cells expressing human ANO1 and SW620 cells at 50 µM; inhibits the proliferation of SW620 cells; reduces the release of histamine, tryptase beta, β-hexosaminidase, TNF-α, and CCL2, as well as inhibits SP-induced cellular degranulation in LAD 2 and mouse primary mast cells; upregulates phosphorylation of SHP-1 and SHP-2 in LAD 2 cells with CD300f knocked down using siRNA at 50 µM; inhibits SP-induced mast cell degranulation and reduces mouse serum levels of histamine, tryptase beta 2, TNF-α, CCL2, and CXCL2 in vivo at 1 or 2 mg/kg |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | dehydro-andrographolide Andrographis ANO 1 TMEM 16A SW 620 TNFα CC CCL CXCL CXC 2 LAD2 SHP1 SHP2 |
Gene, Accession, CAS # | CAS: 134418-28-3 |
Catalog # | 31625-50 |
Price | $318.00 |
Order / More Info | Dehydroandrographolide from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |