NI-42 from CAYMAN CHEMICAL COMPANY
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| Product Name | NI-42 |
| Description | An inhibitor of the BRPF1 bromodomain (IC50 = 7.9 nM); selective for BRPF1 over BRPF2/BRD1, BRPF3, BRD9, and BRD4/BD1 (IC50s = 48, 260, 310, and 4,500 nM, respectively); inhibits the growth of OCI-AML2, Nomo-1, THP-1, KG-1, and MV-4-11 AML cells (GI50s = 1.3, 4.6, 5.7, 7, and 9.9 µM, respectively) and a variety of non-AML cells (GI50s = 1-10 µM); also inhibits the growth of DMS114 lung, HRA-19 colon, and RERF-LC-Sq1 lung cancer cells (GI50s = 16.6, 15.6, and 17.1 µM, respectively) |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | NI42 BRPF 2 3 BRD 9 4 BD OCIAML2 AML Nomo1 THP1 KG1 MV411 411 MV4 nonAML DMS 114 HRA19 RERFLCSq1 RERFLC LCSq1 Sq NCIH1703 H 1703 |
| Gene, Accession, CAS # | CAS: 1884640-99-6 |
| Catalog # | 28293-5 |
| Price | $93.00 |
| Order / More Info | NI-42 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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