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Product Name | LY333531 (hydrochloride) |
Description | A PKCβ inhibitor (IC50s = 4.7 and 5.9 nM for PKCβ1 and PKCβ2, respectively); selective for PKCβ1 and PKCβ2 over PKCα, -γ, -δ, -ε, -ζ, and -η (IC50s = 360, 300, 250, >100,000, and 52 nM, respectively); inhibits GSK3β (IC50 = 39.4 nM); inhibits PMA-induced NET formation in primary human neutrophils at 1 µM; increases the mechanical nociceptive threshold in a rat model of STZ-induced diabetic hyperalgesia |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Ruboxistaurin |
Gene, Accession, CAS # | CAS: 169939-93-9 |
Catalog # | 13964-5 |
Price | $311.00 |
Order / More Info | LY333531 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |