KLH45 from CAYMAN CHEMICAL COMPANY

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Product NameKLH45
DescriptionAn inhibitor of DDHD2 (IC50 = 1.3 nM); selective for DDHD2 over greater than 50 serine hydrolases, including DDHD1 and Sec23ip, but does inhibit ABHD6; inhibits DDHD2 and ABHD6 in Neuro2A cells at 95% at 25 nM; prevents increases in TAG hydrolase activity in HEK293T cell lysates expressing DDHD2 and incubated with a radiolabeled TAG substrate at 2 µM; decreases TAG levels in mouse CNS at 20 mg/kg twice per day for four days; reverses DDHD2-induced lipid droplet reduction in COS-7 cells expressing species recombinant DDHD2 and loaded with oleic acid at 2 µM
Size25 mg
Concentrationn/a
Applicationsn/a
Other NamesDDHD-2-1 serine hydrolase ABHD-6 TAG KLH-45 Sec-23ip HEK-293 Neuro-2A COS7
Gene, Accession, CAS #CAS: 1632236-44-2
Catalog #19889-25
Price$365.00
Order / More InfoKLH45 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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