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Product Name | MST-312 |
Description | A telomerase inhibitor (IC50 = 0.67 µM in a TRAP assay); selective for telomerase over DNA polymerase (3 µM); inhibits growth of U937 cells (GI50 = 1.7 µM); reduces cell number and expression of the proliferation marker MIB-1 as well as increases DNA damage in primary pediatric ependymoma tumor cells; decreases survival of H460 and H1299 NSCLC cells; reduces tumor size by 70% in an H460 mouse xenograft model (40 mg/kg); inhibits replication of HSV-2 and a clinical isolate of HSV-1; decreases accumulation of early and late viral proteins in HEp-2 cells infected with HSV-1 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Telomerase Inhibitor IX |
Gene, Accession, CAS # | CAS: 368449-04-1 |
Catalog # | 24301-10 |
Price | $166.00 |
Order / More Info | MST-312 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |