Ro 60-0175 from CAYMAN CHEMICAL COMPANY
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| Product Name | Ro 60-0175 |
| Description | A 5-HT2 agonist; stimulates increases in intracellular calcium levels in CHO-K1 cells expressing human 5-HT2A, 5-HT2B, and 5-HT2C (EC50s = 447, 0.9, and 32 nM, respectively); selective for human 5-HT2A and 5-HT2C (Kis = 32 and 1 nM, respectively) over human 5-HT1A, 5-HT1D, 5-HT6, and 5-HT7, rat 5-HT1B and 5-HT3, and guinea pig 5-HT4 receptors (Kis = ≥1,995 nM), as well as adenosine A1 and A2, histamine H1-3, dopamine D1-5, α1-, α2-, and β1-adrenergic, M1-5 muscarinic, nicotinic, kainate, AMPA, and μ-, δ-, and κ-opioid receptors (IC50s = >1,000 nM), but does bind to β2-adrenergic receptors (IC50 = 251 nM); increases plasma levels of corticosterone, oxytocin, and prolactin in rats (ED50s = 2.43, 4.19, and 4.03 mg/kg, respectively) |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 169675-08-5 600175 5HT 5HT2 CHOK1 H2H3 D2 D3 D4 D5 M2 M3 M4 M5 pro lactin volinan serin OR35030 ORG 35030 |
| Gene, Accession, CAS # | CAS: 169675-09-6 |
| Catalog # | 29520-1 |
| Price | $32 |
| Order / More Info | Ro 60-0175 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
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