ML-382 from CAYMAN CHEMICAL COMPANY
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| Product Name | ML-382 |
| Description | An MRGPRX1 positive allosteric modulator; potentiates BAM 22P (8-22)-induced activation of MRGPRX1 in HEK293 cells expressing the human receptor (EC50 = 0.19 µM) but does not potentiate PAMP-induced activation of MRGPRX2 in HEK293 cells expressing the human receptor at 5 µM; selective for MRGPRX1 over a panel of 68 GPCRs, ion channels, and transporters at 10 µM; enhances BAM 22P (8-22)-induced inhibition of high-voltage-activated ICa in dorsal root ganglion neurons isolated from transgenic mice expressing human MRGPRX1 at 5 µM; intrathecal administration decreases formalin-induced paw licking and shaking in MRGPRX1 transgenic mice at 25 µM/animal |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | VU0485891 |
| Gene, Accession, CAS # | CAS: 1646499-97-9 |
| Catalog # | 36668-5 |
| Price | $100.00 |
| Order / More Info | ML-382 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY