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Product Name | CPS2 |
Description | A PROTAC that drives Cdk2 degradation; selectively degrades Cdk2 (IC50 = 24 nM) over seven additional CDKs at 500 nM but also degrades Aurora A kinase and IKZF1 at 250 nM; reduces Cdk2 levels and increases the percentage of cells expressing CD11b, a marker of differentiation, in primary AML cells; decreases proliferation without reducing the viability of, as well as induces differentiation in, primary HSCs |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | CPS-2 JNJ7706621 Cdk CD-11b |
Gene, Accession, CAS # | CAS: 2756741-90-7 |
Catalog # | 40457-10 |
Price | $358.00 |
Order / More Info | CPS2 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |