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Product Name | Sulfisoxazole |
Description | A sulfonamide antibiotic and nonpeptide ET receptor antagonist (IC50s = 0.6 and 22 µM for the ETA and ETB receptors, respectively); inhibits the growth of Gram-positive and Gram-negative bacteria in vitro, including S. pneumoniae, B. subtilis, S. epidermidis, E. coli, and K. pneumoniae (MICs = 1.95, 0.98, 7.81, 62.5, and 7.81 µg/mL, respectively); inhibits phosphoinositide turnover stimulated by ET-1 in TE671 cells; inhibits ET-induced contraction of rat pulmonary artery rings ex vivo at 0.1 and 1 mM; reduces atrial natriuretic peptide levels in myocytes and plasma and increases survival in a rat model of pulmonary hypertension induced by MCT at 1,000 mg/kg per day; blocks MCT-induced increases in pulmonary artery blood pressure at 300 and 1,000 mg/kg |
Size | 10 g |
Concentration | n/a |
Applications | n/a |
Other Names | NSC 13120|NSC 33807|NSC 38588|NSC 683536|Sulfafurazole |
Gene, Accession, CAS # | CAS: 127-69-5 |
Catalog # | 25980-10 |
Price | $195.00 |
Order / More Info | Sulfisoxazole from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |