PRLX-93936 from CAYMAN CHEMICAL COMPANY
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| Product Name | PRLX-93936 |
| Description | An erastin analog that has antitumor activity; inhibits the HIF-1 signaling pathway under hypoxic conditions (IC50 = 0.09 µM in a cell-based reporter assay); inhibits hypoxia-induced increases in HIF-1α expression in ME-180 cervical cancer cells at 1 µM; inhibits the growth of HT-1080 fibrosarcoma, OVCAR-5 ovarian cancer, BJELR tumorigenic primary fibroblast, and PANC-1 pancreatic cancer cells (IC50s = <100 nM); inhibits tumor growth in PANC-1 and HT-1080 xenograft models at 50 mg/kg and induces tumor regression at 100 mg/kg |
| Size | 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | PRLX93936 anti-tumor HIF1 HIF1α ME180 HT1080 OVCAR5 PANC1 |
| Gene, Accession, CAS # | CAS: 903499-49-0 |
| Catalog # | 25631-25 |
| Price | $887 |
| Order / More Info | PRLX-93936 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY