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Product Name | Netupitant |
Description | An NK1 receptor antagonist (Ki = 0.95 nM); selective for human NK1 over human NK2 and NK3 and rat NK1 (Kis = >1,500 nM); selective for NK1 over 50 G protein-coupled receptors, monoamine transporters, and ion channels when used in the nanomolar range; decreases the maximal response to substance P in isolated guinea pig ileum; inhibits substance P-induced scratching, biting, and licking in mice at doses of 1-10 mg/kg; decreases NK agonist-induced foot tapping in gerbils (ID50s = 1.5 mg/kg, i.p., or 0.5 mg/kg, oral). |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Ro 67-31898/000 |
Gene, Accession, CAS # | CAS: 290297-26-6 |
Catalog # | 23809-25 |
Price | $167.00 |
Order / More Info | Netupitant from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |