XL147 from CAYMAN CHEMICAL COMPANY
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| Product Name | XL147 |
| Description | A class I PI3K inhibitor (IC50s = 0.039, 0.036, 0.023, and 0.383 µM for p110α, -δ, -γ, and -β, respectively); selective for class I PI3Ks over Vps34, DNA-PK, and mTOR (IC50s = 6.974, 4.75, and >15 µM, respectively); inhibits proliferation of MCF-7 and PC3 cells (IC50s = 9.669 and 16.492 µM, respectively); reduces tumor growth in a BT474 breast cancer mouse xenograft model when administered alone or in combination with trastuzumab or lapatinib |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Pilaralisib|SAR245408 |
| Gene, Accession, CAS # | CAS: 934526-89-3 |
| Catalog # | 18011-5 |
| Price | $81.00 |
| Order / More Info | XL147 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY