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Product Name | CAY10723 (hydrochloride) |
Description | A PAD2 inhibitor (EC50 = 9.5 µM in a cellular target engagement assay); ~1.6-, ~47-, and ~15-fold selective for PAD2 over PAD1, PAD3, and PAD4, respectively; inhibits histone H3 citrullination in HEK293T cells expressing human PAD2 (EC50 = 0.4 µM); inhibits fibrinogen citrullination in the presence of isolated human PMNs or synovial fluid from patients with rheumatoid arthritis at 20 µM; decreases IFN-γ production in isolated human CD4+ T cells at 25 µM |
Size | 500 µg |
Concentration | n/a |
Applications | n/a |
Other Names | AFM30a|AMF30a |
Gene, Accession, CAS # | n/a |
Catalog # | 38018-500 |
Price | $101.00 |
Order / More Info | CAY10723 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |