CP 91,149 from CAYMAN CHEMICAL COMPANY

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Product NameCP 91,149
DescriptionAn inhibitor of LGPa, MGPa, and MGPb (IC50s = 0.13, 0.2, and 0.3 µM, respectively, in the presence of glucose); inhibits glucagon-stimulated glycogenolysis in primary human hepatocytes (IC50 = 2.1 µM) and increases glycogen synthesis in rat hepatocytes at a concentration of 2.5 µM in the presence of 5 mM glucose; inhibits brain GP (IC50 = 0.5 µM) and glycogen accumulation and proliferation of A549 NSCLC cells that express endogenous brain GP (30 µM); lowers plasma glucose level in diabetic ob/ob mice within 3 hours of administration without producing hypoglycemia, but has no effect on normoglycemic, non-diabetic mice (25 mg/kg, p.o.)
Size10 mg
Concentrationn/a
Applicationsn/a
Other Names91149 CP91149
Gene, Accession, CAS #CAS: 186392-40-5
Catalog #17709-10
Price$109.00
Order / More InfoCP 91,149 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

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