AS-1892802 from CAYMAN CHEMICAL COMPANY
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| Product Name | AS-1892802 |
| Description | A potent ROCK inhibitor (IC50s = 122, 52, and 57 nM for human ROCK1, ROCK2, and rat ROCK2, respectively); selective for ROCK1 and 2 over a panel of 167 kinases and a panel of 63 ion channels, receptors, and enzymes at a concentration of 10 µM; inhibits PKACα and PRKX (IC50s = 200 and 325 nM, respectively); reduces weight imbalance deficits (ED50 = 0.15 mg/kg) in rats in a monoiodoacetate-induced model of non-inflammatory arthritis; has analgesic-like effects in a rat model of streptozotocin-induced diabetic neuropathy; reduces cartilage damage and weight imbalance deficits in a rat model of osteoarthritis., |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | AS1892802 ROCK-1 PKAC-α |
| Gene, Accession, CAS # | CAS: 928320-12-1 |
| Catalog # | 14978-5 |
| Price | $172.00 |
| Order / More Info | AS-1892802 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
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