BI-409306 from CAYMAN CHEMICAL COMPANY

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Product NameBI-409306
DescriptionA potent and selective PDE9A inhibitor (IC50s = 65 and 168 nM for the human and rat enzymes, respectively); selective for PDE9A over PDE2A, -3A, -4B, -5A, -6AB, -7A and -10A and 95 non-PDE targets at 10 µM but inhibits human PDE1A and PDE1C (IC50s = 1.45 and 1.17 µM, respectively); increases mouse striatal cGMP levels at 0.5 mg/kg in combination with MK-801; enhances LTP in hippocampal slices and reverses MK-801-induced working memory deficits in mice at 0.007-2.5 mg/kg
Size25 mg
Concentrationn/a
Applicationsn/a
Other Names2231017-68-6 BI409306 MK801 PDE-9A PDE-2A
Gene, Accession, CAS #CAS: 1189767-28-9
Catalog #30375-25
Price$745.00
Order / More InfoBI-409306 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
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http://www.caymanchem.com

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