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Product Name | BI-409306 |
Description | A potent and selective PDE9A inhibitor (IC50s = 65 and 168 nM for the human and rat enzymes, respectively); selective for PDE9A over PDE2A, -3A, -4B, -5A, -6AB, -7A and -10A and 95 non-PDE targets at 10 µM but inhibits human PDE1A and PDE1C (IC50s = 1.45 and 1.17 µM, respectively); increases mouse striatal cGMP levels at 0.5 mg/kg in combination with MK-801; enhances LTP in hippocampal slices and reverses MK-801-induced working memory deficits in mice at 0.007-2.5 mg/kg |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2231017-68-6 BI409306 MK801 PDE-9A PDE-2A |
Gene, Accession, CAS # | CAS: 1189767-28-9 |
Catalog # | 30375-25 |
Price | $745.00 |
Order / More Info | BI-409306 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |