NCB-0846 from CAYMAN CHEMICAL COMPANY
Search, find, compare suppliers for NCB-0846 products.
| Edit | |
|---|---|
| Product Name | NCB-0846 |
| Description | A TNIK inhibitor (IC50 = 21 nM); selective for TNIK over a panel of 46 kinases but does inhibit FLT3, JAK3, PDGFRα, TrkA, Cdk2/CycA2, and HGK by >80% at 100 nM; inhibits phosphorylation of TCF4 and autophosphorylation of TNIK in cell-based assays at 3 µM; inhibits the growth and colony formation of HCT116 cells in two-dimensional growth and soft-agar assays, respectively, as well as reduces tumor growth in an HCT116 mouse xenograft model; reduces tumor growth in PDX mouse models of colon cancer at 50 and 100 mg/kg |
| Size | 50 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | NPC0846 TRAF FLT JAK PDGFR Cdk CycA TCF HCT-116 auto-phosphorylation |
| Gene, Accession, CAS # | CAS: 1792999-26-8 |
| Catalog # | 33268-50 |
| Price | $881.00 |
| Order / More Info | NCB-0846 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY