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Product Name | Briciclib |
Description | An eIF4E inhibitor; inhibits proliferation of JEKO-1 and Mino MCL, MCF-7 and MDA-MB-231 breast, AGS gastric, and OE19, OE33, and LFO-1 esophageal cancer cell lines (GI50s = 9.8-12.2 nM); reduces expression of cyclin D1 and c-Myc, markers of eIF4E activity, in breast and MCL cancer cell lines in a dose-dependent manner; induces expression of the pro-apoptotic proteins p53 and cleaved caspase-3, |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | ON-014185 |
Gene, Accession, CAS # | CAS: 865783-99-9 |
Catalog # | 22989-5 |
Price | $161.00 |
Order / More Info | Briciclib from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |